Chapter

Pharmacotherapy: non-statin drugs

Edited by D. John Betteridge

in Hyperlipidaemia

Published on behalf of Oxford University Press

ISBN: 9780199543502
Published online October 2011 | e-ISBN: 9780199607204 | DOI: http://dx.doi.org/10.1093/med/9780199543502.003.0008

Series: Oxford Cardiology Library

Pharmacotherapy: non-statin drugs

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• Non-statin drugs do not have a large volume of data from randomized clinical trials (RCTs) to guide therapy but reasonable evidence exists for the fibrates, gemfibrozil, nicotinic acid, and the resins. • Non-statin drugs may be indicated in patients intolerant of statins or in whom statins are contraindicated. • Non-statin drugs may be added to statin therapy to obtain further effects on low-density lipoprotein (LDL) if treatment goals are not achieved on maximum-tolerated statin dose. • Non-statin drugs may be added to statin therapy to obtain further effects in increasing high-density lipoprotein (HDL) and reducing triglyceride.

Chapter.  5569 words. 

Subjects: Pharmacology

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