Chapter

Migraine

Messoud Ashina

in Migraine and other Primary Headaches

Published on behalf of Oxford University Press

ISBN: 9780199545148
Published online May 2011 | e-ISBN: 9780199607242 | DOI: http://dx.doi.org/10.1093/med/9780199545148.003.0006

Series: Oxford Pain Management Library

Migraine

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• Migraine is a neurovascular disorder with a genetic component. • Migraine aura is caused by cortical spreading depression. • Migraine headache is due to activation of perivascular nociceptors and subsequent plastic changes in the central nervous system. • Nitric oxide and calcitonin gene-related peptide play a key role in pathophysiology.

Chapter.  2445 words.  Illustrated.

Subjects: Clinical Medicine

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