Cluster and other trigeminal autonomic cephalalgias

Gennaro Bussone and Massimo Leone

in Migraine and other Primary Headaches

Published on behalf of Oxford University Press

ISBN: 9780199545148
Published online May 2011 | e-ISBN: 9780199607242 | DOI:

Series: Oxford Pain Management Library

Cluster and other trigeminal autonomic cephalalgias

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• The first step in management is to reassure the patient that the condition is benign and to provide accurate information about it. • There are two pharmacological approaches: acute and prophylactic. • For cluster headache, the first choice acute treatment is the selective 5-HT1B/1D receptor agonist sumatriptan. • A number of different drug options are available for prophylaxis. • The choice of prophylactic drug is influenced by previous response, previous side-effects, contraindications, duration of symptoms, and the age and lifestyle of the patient. • If a severe attack occurs notwithstanding prophylaxis, acute medications should be employed. • Patients with chronic trigeminal autonomic cephalalgias who do not respond to, or have major contraindications to, prophylactic treatments may be candidates for surgical approaches.

Chapter.  2601 words. 

Subjects: Clinical Medicine

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