Chapter

Pathophysiology of hypertension

Sunil Nadar

in Hypertension

Published on behalf of Oxford University Press

ISBN: 9780199547579
Published online May 2011 | e-ISBN: 9780199607266 | DOI: http://dx.doi.org/10.1093/med/9780199547579.003.0002

Series: Oxford Cardiology Library

Pathophysiology of hypertension

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Hypertension is a complex disease with many factors contributing to its development and maintenance. Increased circulatory volume and increased peripheral resistance are the main pathophysiological mechanisms. The reninangiotensinaldosterone system along with abnormalities in the renal tubules also play a part. Endothelial activation, dysfunction, and damage that are seen in hypertension are both a cause and effect of the raised blood pressure and contribute significantly to the maintenance of high blood pressure.

Chapter.  1731 words.  Illustrated.

Subjects: Cardiovascular Medicine

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