Chapter

ACE inhibitors in hypertension

Sunil Nadar

in Hypertension

Published on behalf of Oxford University Press

ISBN: 9780199547579
Published online May 2011 | e-ISBN: 9780199607266 | DOI: http://dx.doi.org/10.1093/med/9780199547579.003.0014

Series: Oxford Cardiology Library

ACE inhibitors in hypertension

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Angiotensin-converting enzyme (ACE) inhibitors decrease the production of angiotensin II, reduce sympathetic nervous system activity, and increase bradykinin levels. ACE inhibitors are effective antihypertensive agents and slow the progression of target organ damage including various nephropathies and left ventricular hypertrophy and heart failure. They are also useful in reducing the mortality post-myocardial infarction and in high-risk coronary or peripheral vascular disease patients. The main side effects of ACE inhibitors include cough, angioedema, hyperkalaemia, and worsening of renal functions especially in the presence of renal artery stenosis.

Chapter.  2503 words. 

Subjects: Cardiovascular Medicine

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