Hypertension in diabetic patients

Vasudevan A Raghavan

in Hypertension

Published on behalf of Oxford University Press

ISBN: 9780199547579
Published online May 2011 | e-ISBN: 9780199607266 | DOI:

Series: Oxford Cardiology Library

Hypertension in diabetic patients

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Hypertension occurs frequently in diabetics and is often associated with macro and microvascular complications. Volume expansion, hyperinsulinaemia, the reninangiotensin system, and increased arterial stiffness play a role in the pathogenesis of the complications of the hypertensive diabetic patient. Management of these patients encompasses reduction of cardiovascular risk and the reduction of target organ damage (TOD). The target blood pressure values are lower than for non-diabetic hypertensive patients. Angiotensin-converting enzyme (ACE) inhibitors or angiotensin receptor blockers (ARBs) should be used as first-line therapy, either as monotherapy or usually in combination with other agents to help reduce blood pressure and prevent renal complications.

Chapter.  4423 words.  Illustrated.

Subjects: Cardiovascular Medicine

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