Smoking cessation

Onn Min Kon and Susannah A.A. Bloch

in Chronic Obstructive Pulmonary Disease (COPD)

Published on behalf of Oxford University Press

ISBN: 9780199549146
Published online May 2011 | e-ISBN: 9780199607273 | DOI:

Series: Oxford Respiratory Medicine Library

Smoking cessation

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• Smoking cessation is currently the only intervention that causes a slowing in the natural history of an accelerated loss of forced expiratory volume in 1s (FEV1) in COPD. • The addictive properties of nicotine in tobacco are mediated primarily through the release of dopamine in the nucleus accumbens via nicotinic receptors. • Smoking advice should be carried out regularly by all health professionals and has been shown to be effective. • Both behavioural therapy and pharmacological therapies have been shown to be effective in achieving smoking cessation. • Nicotine replacement, bupropion, and varenicline are first-line agents that increase the likelihood of successful smoking cessation.

Chapter.  2551 words. 

Subjects: Respiratory Medicine and Pulmonology

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