Chapter

Chronic kidney disease and infectious disease

Kar Neng Lai, Andrew S.H. Lai and Sydney C.W. Tang

in Chronic Kidney Disease

Published on behalf of Oxford University Press

Published in print December 2009 | ISBN: 9780199549313
Published online February 2013 | e-ISBN: 9780191763465 | DOI: http://dx.doi.org/10.1093/med/9780199549313.003.0006

Series: Oxford Clinical Nephrology Series

Chronic kidney disease and infectious disease

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The relationship between infection and chronic kidney disease is an interesting subject because of the different mechanisms of glomerular and tubulointerstitial injury and heterogeneous clinicopathological patterns are operative. The aetiological role of some infective organisms is still undefined. Early identification and eradication of the infective organism are essential for preventing the development of chronic kidney disease. A continuous supply of microbial antigen and host antibody perpetuate the immunologic injury to the kidney. In the future, molecular biology techniques hold the key in further documentation of the precise nature of the infective organism in the pathogenesis of infection-related nephropathy.

Chapter.  6975 words. 

Subjects: Nephrology ; Infectious Diseases

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