Nico L. Leenders

in Parkinson's Disease

Published on behalf of Oxford University Press

ISBN: 9780199550630
Published online May 2011 | e-ISBN: 9780199607297 | DOI:

Series: Oxford Neurology Library


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• Neuroimaging by itself can not establish a diagnosis of Parkinson’s Disease (PD) or related disorders. However, in the appropriate clinical context it can provide key information • MRI or CT scans are useful in excluding comorbidity or proving alternative causes of parkinsonisms, but do not contribute to making a diagnosis of PD • Dopaminergic radiotracers as used in SPECT and PET brain scanning are extremely useful within the right clinical context, but need to be applied and interpreted with caution • Cerebral glucose metabolism as measured using PET scanning can be applied usefully in neurodegenerative brain diseases to guide the clinician in the complex field of parkinsonian conditions or dementias • Sonography is a promising method which may obtain a place in early diagnosis of PD, but overlap with healthy controls and other conditions can be considerable and in a fairly large number of subjects it is not possible to obtain an adequate acoustical window.

Chapter.  4801 words.  Illustrated.

Subjects: Neurology

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