Surgery in Parkinson’s disease

Irene Martinez-Torres and Patricia Limousin

in Parkinson's Disease

Published on behalf of Oxford University Press

ISBN: 9780199550630
Published online May 2011 | e-ISBN: 9780199607297 | DOI:

Series: Oxford Neurology Library

Surgery in Parkinson’s disease

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• Surgical treatment for Parkinson’s disease is currently dominated by deep brain stimulation (DBS) • The subthalamic nucleus (STN) has become the target most commonly used in DBS as it improves a wide range of symptoms • Thalamic or pallidal stimulation still have their places and should not be ignored • Ablative procedures are considered for selected patients, when DBS is contraindicated or not available • Neuroprotective and restorative approaches, such as cell transplantation or gene therapy are still in development and might in the future replace DBS.

Chapter.  3290 words.  Illustrated.

Subjects: Neurology

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