Prevention of thrombosis in orthopaedic surgery

David Warwick

in Oxford Textbook of Trauma and Orthopaedics

Second edition

Published on behalf of Oxford University Press

Published in print August 2011 | ISBN: 9780199550647
Published online April 2011 | e-ISBN: 9780199608249 | DOI:

Series: Oxford Textbooks

Prevention of thrombosis in orthopaedic surgery

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  • Trauma and Orthopaedic Surgery
  • Haematology


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The risk–benefit of thromboprophylaxis in orthopaedic surgery remains unclear

Some conditions, such as major trauma, carry a much higher risk than others, such as routine knee replacement

Some patients appear to be genetically more predisposed than others

In trials of efficacy of thromboembolism, the use of deep vein thrombosis as a surrogate endpoint for death from a pulmonary embolus may not be completely reliable

There is a variety of mechanical and chemical methods available, each of which has real and potential advantages as well as real and potential dangers

Even the length of time that a patient is at risk after major surgery is unclear

Clinicians should adhere to guidelines where possible.

Chapter.  5258 words.  Illustrated.

Subjects: Trauma and Orthopaedic Surgery ; Haematology

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