Inflammatory connective tissue disease

Catherine Swales

in Oxford Textbook of Trauma and Orthopaedics

Second edition

Published on behalf of Oxford University Press

Published in print August 2011 | ISBN: 9780199550647
Published online April 2011 | e-ISBN: 9780199608249 | DOI:

Series: Oxford Textbooks

Inflammatory connective tissue disease

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Systemic lupus erythematosus (SLE) is the commonest multisystem connective tissue disease

All patients with SLE are antinuclear antibody (ANA) positive, but not all ANA-positive patients have SLE

Renal lupus carries a high mortality and requires aggressive immunosuppression

Dermatomyositis may be associated with malignancy in the elderly

The vasculitides are classified according to vessel size and ANCA (antineutrophil cytoplasmic antibody) profile

Therapy for vasculitis includes corticosteroids, steroid-sparing agents, and cytotoxics.

Chapter.  2178 words.  Illustrated.

Subjects: Trauma and Orthopaedic Surgery ; Rheumatology

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