Chapter

Insulin treatment and transplantation

David Levy

in Type 1 Diabetes

Published on behalf of Oxford University Press

ISBN: 9780199553211
Published online September 2011 | e-ISBN: 9780191740190 | DOI: http://dx.doi.org/10.1093/med/9780199553211.003.0004

Series: Oxford Diabetes Library

Insulin treatment and transplantation

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• The standard for basal and prandial insulin replacement is either multiple dose insulin (MDI) or continuous subcutaneous insulin infusion (CSII), both of which can give near-normoglycaemia (A1C ∼6.5 to 7.0%). • Careful implementation of MDI or CSII with a multidisciplinary team is probably more important to success than the specific types of insulin used. • CSII can give remarkable results in some groups of patients. • Only pancreas or islet transplantation can deliver true physiological insulin replacement. • The results of pancreas and islet cell transplantation are continuously improving, and currently offer the only reliable technique for stabilizing and reversing microvascular, and possibly macrovascular complications.

Chapter.  6637 words.  Illustrated.

Subjects: Endocrinology and Diabetes

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