Chapter

Microvascular complications

David Levy

in Type 1 Diabetes

Published on behalf of Oxford University Press

ISBN: 9780199553211
Published online September 2011 | e-ISBN: 9780191740190 | DOI: http://dx.doi.org/10.1093/med/9780199553211.003.0005

Series: Oxford Diabetes Library

Microvascular complications

More Like This

Show all results sharing this subject:

  • Endocrinology and Diabetes

GO

Show Summary Details

Preview

• Hyperglycaemia damages the microvasculature through several mechanisms; strict control of hyperglycaemia remains overwhelmingly the most important factor in preventing and reversing microvascular complications in Type 1 diabetes. • End-stage microvascular complications (blindness, end-stage renal failure, amputations for neuropathic foot complications) are probably becoming less common; no single responsible factor can be identified. • The Diabetes Control and Complications Trial and the Epidemiology of Diabetes Interventions and Complications follow-up (1982–2006) confirmed dramatic and long-lasting benefits of intensive therapy on microvascular complications (40–60% risk reduction) with A1C consistently maintained at ∼7% for ∼7 yrs.

Chapter.  10752 words.  Illustrated.

Subjects: Endocrinology and Diabetes

Full text: subscription required

How to subscribe Recommend to my Librarian

Buy this work at Oxford University Press »

Users without a subscription are not able to see the full content. Please, subscribe or login to access all content.