Pharmacological aids to smoking cessation

Stuart Rees and Keir E. Lewis

in Smoking Cessation

Published on behalf of Oxford University Press

ISBN: 9780199556250
Published online May 2011 | e-ISBN: 9780199607327 | DOI:

Series: Oxford Respiratory Medicine Library

Pharmacological aids to smoking cessation

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• Nicotine replacement therapy approximately doubles the chances of quitting regardless of additional support. • Bupropion and varenicline are effective non-nicotine-based products. • Second-line agents include nortriptyline and clonidine. • Choice of drug is often determined by smokers’ preferences which are affected by previous attempts, side-effect profiles, and potential drug interactions. • Tobacco smoke increases the activity of several liver enzymes, so altered drug pharmacokinetics and pharmacodynamics should be considered when a patient stops smoking.

Chapter.  3979 words. 

Subjects: Respiratory Medicine and Pulmonology

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