Chapter

Comorbidity and complications of RA

Nicola Goodson and Raashid Luqmani

in Rheumatoid Arthritis

Published on behalf of Oxford University Press

ISBN: 9780199556755
Published online May 2011 | e-ISBN: 9780199607334 | DOI: http://dx.doi.org/10.1093/med/9780199556755.003.0008

Series: Oxford Rheumatology Library

Comorbidity and complications of RA

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• Patients with rheumatoid arthritis have a reduced life expectancy • The most common attributed cause of death in patients with RA is cardiovascular disease • Infection, pulmonary, gastrointestinal and renal disease account for excess deaths in patients with RA compared to the general population • Suppressing disease activity and reducing traditional cardiovascular risk factors may improve survival in RA • Increased rates of infection, osteoporosis, depression respiratory, gastrointestinal and renal disease all contribute to the co-morbid disease burden in these patients • Serious complications and co-morbid disease may cause rheumatological emergencies including: acute infection, cardiovascular events, peptic ulceration and gastrointestinal bleeding, cervical spine disease with spinal cord compression, lymphoproliferative malignancy, rheumatoid vasculitis and respiratory failure.

Chapter.  5076 words.  Illustrated.

Subjects: Rheumatology

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