Chemotherapy for metastatic prostate cancer

Cora N Sternberg and Guru Sonpavde

in Systemic Treatment of Prostate Cancer

Published on behalf of Oxford University Press

ISBN: 9780199561421
Published online May 2011 | e-ISBN: 9780199607372 | DOI:

Series: Oxford Oncology Library

Chemotherapy for metastatic prostate cancer

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• Docetaxel-based chemotherapy has been shown to modestly extend life, relieve pain, and improve the quality of life in patients with metastatic castration-resistant prostate cancer • Current trials are attempting to build on the backbone of docetaxel by combining it with novel biologic agents • Trials are also investigating the role of docetaxel for earlier stages of prostate cancer • No standard second-line chemotherapy exists and such patients are candidates for trials. The increased understanding of the mechanisms of progressive castration-resistant prostate cancer is being translated into an increasing pipeline of novel therapies.

Chapter.  3410 words. 

Subjects: Clinical Oncology

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