Complex regional pain syndrome

Dudley Bush

in Neuropathic Pain

Second edition

Published on behalf of Oxford University Press

ISBN: 9780199563678
Published online May 2011 | e-ISBN: 9780199607426 | DOI:

Series: Oxford Pain Management Library

Complex regional pain syndrome

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• Complex regional pain syndrome is the current name for the conditions previously called reflex sympathetic dystrophy (now CRPS type I) and causalgia (now CRPS type II). • It occurs in distal limbs following trauma or surgery, is not related to intensity of initial insult, and is idiopathic in 10% of cases. There are around 10,000 cases in the UK and it is four times more common in females. • Mechanisms underlying CRPS are complex but may involve neurogenic inflammation. • Weakness and autonomic changes commonly accompany pain. • Treatment is based on relief of pain (with co-analgesics, opioids, and neuromodulation) combined with restoration of function, so early referral and treatment is essential to prevent irreversible trophic changes and contractures.

Chapter.  2893 words.  Illustrated.

Subjects: Anaesthetics ; Pain Medicine

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