Cancer neuropathic pain

Fliss E. Murtagh and Irene J. Higginson

in Neuropathic Pain

Second edition

Published on behalf of Oxford University Press

ISBN: 9780199563678
Published online May 2011 | e-ISBN: 9780199607426 | DOI:

Series: Oxford Pain Management Library

Cancer neuropathic pain

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• Around a third of cancer pains may have a neuropathic component and mixed pathology is more usual than ‘pure’ neuropathic pain • Compression and infiltration of nerves by tumour are the most common causes • Treatment-induced damage (chemotherapy-induced neuropathy, radiation plexitis, surgical trauma) and paraneoplastic syndromes are less common causes • Cancer patients are generally older and frailer than other chronic pain patients and may be more vulnerable to adverse drug effects • First-line treatment with opioids is usual in this context but co-analgesics are almost certainly needed in addition.

Chapter.  2955 words. 

Subjects: Anaesthetics ; Pain Medicine

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