Chapter

Lupus membranous nephropathy<fc>1</fc>

Howard A. Austin III, Gabor G. Illei and James E. Balow

in Lupus Nephritis

Second edition

Published on behalf of Oxford University Press

Published in print November 2010 | ISBN: 9780199568055
Published online November 2012 | e-ISBN: 9780191753374 | DOI: http://dx.doi.org/10.1093/med/9780199568055.003.0007

Series: Oxford Clinical Nephrology Series

Lupus membranous nephropathy<fc>1</fc>

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Lupus membranous nephropathy (LMN) is characterized by widespread subepithelial and/or intramembranous immune deposits, diffuse glomerular capillary wall thickening, and, frequently, mesangial expansion. These morphological attributes are observed in approximately 10–20% of lupus patients who develop clinically significant renal involvement during the course of their disease. Furthermore, LMN is one of the most common causes of secondary membranous nephropathy, accounting for approximately 20% of those patients. Comparable to people with idiopathic membranous nephropathy, individuals with LMN are at increased long-term risk for end stage renal disease (ESRD) and complications of the nephrotic syndrome.

Chapter.  12384 words.  Illustrated.

Subjects: Nephrology

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