Coronary physiology in clinical practice

Olivier Muller and Bernard De Bruyne

in Oxford Textbook of Interventional Cardiology

Published on behalf of Oxford University Press

ISBN: 9780199569083
Published online July 2011 | e-ISBN: 9780199697816 | DOI:

Series: Oxford Textbooks

Coronary physiology in clinical practice

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  • Radiology
  • Cardiovascular Medicine


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The goal of any treatment is to improve patients’ prognosis and/or symptoms. Accordingly, the goal of any diagnostic tool is to guide decision-making to apply optimal treatment in individual patients. Any diagnostic tool not fulfilling these requirements should not be used in patients. Keeping this in mind, this chapter will briefly review what is often referred to as ‘invasive coronary physiology’.

As opposed to anatomical (also referred to as ‘morphologic’) approaches, physiological (‘functional’) measurements assess the function of the coronary circulation. The function of the coronary arterial circulation is to provide nutrients to the myofibrils. Accessorily, the coronary arteries play a role in diastolic function (turgor effect). No other organ is so dependent on the function of the organ it perfuses.

The combination of an accurate anatomic assessment and precise functional information is indispensable to tailor the treatment of patients with suspected or known coronary artery disease.

Chapter.  9022 words.  Illustrated.

Subjects: Radiology ; Cardiovascular Medicine

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