Chapter

Hypercholesterolaemia and risk assessment

Paul Nicholls and Ian Young

in Lipid Disorders

Published on behalf of Oxford University Press

ISBN: 9780199569656
Published online May 2011 | e-ISBN: 9780199607464 | DOI: http://dx.doi.org/10.1093/med/9780199569656.003.0006

Series: Oxford Cardiology Library

Hypercholesterolaemia and risk assessment

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• In patients with established vascular disease or very high risk (secondary prevention), the aim should be to reduce total cholesterol (TC) to <5 mmol/L and low-density lipoprotein cholesterol (LDL-C) to <3 mmol/L. • Ideal levels are TC <4 mmol/L and LDL-C <2 mmol/L, but these may not be achievable in everybody. • In patients with no known vascular disease (primary prevention), the decision to treat depends on the individual ’ s risk profile, but the targets are the same. • A holistic approach includes assessment of other risk factors as well, such as hypertension, smoking, diabetes, or obesity.

Chapter.  1051 words.  Illustrated.

Subjects: Cardiovascular Medicine

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