Chapter

Pathophysiology of Alzheimer’s disease

Shelley J. Allen and David Dawbarn

in Alzheimer's Disease

Published on behalf of Oxford University Press

Published in print March 2009 | ISBN: 9780199569854
Published online October 2011 | e-ISBN: 9780191739637 | DOI: http://dx.doi.org/10.1093/med/9780199569854.003.0004

Series: Oxford Neurology Library

Pathophysiology of Alzheimer’s disease

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Alzheimer’s disease (AD) is a progressive dementia with loss of neurons and the presence of two main microscopic neuropathological hallmarks: extracellular amyloid plaques and intracellular neurofibrillary tangles

Early onset AD, the rare familial form, is the result of a mutation in one of three genes: ...

Chapter.  3256 words.  Illustrated.

Subjects: Neurology

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