Chapter

Idiopathic pulmonary arterial hypertension

Stephen F Crawley and Andrew J Peacock

in Pulmonary Arterial Hypertension

Published on behalf of Oxford University Press

ISBN: 9780199572632
Published online January 2012 | e-ISBN: 9780199607495 | DOI: http://dx.doi.org/10.1093/med/9780199572632.003.0006

Series: Oxford Cardiology Library

Idiopathic pulmonary arterial hypertension

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• IPAH is a rare but serious condition, for which there is currently no cure • It can present at any age and is more common in females • Left untreated survival rates are very poor • Three classes of disease targeted therapy have recently been introduced, endothelin antagonists, phosphodiesterase inhibitors, and prostanoids • These new treatments improve symptoms and exercise capacity, and in the case of prostanoids improve survival • Many patients will progress to combination therapy or need surgical intervention.

Chapter.  3502 words.  Illustrated.

Subjects: Cardiovascular Medicine

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