Other causes of pulmonary hypertension

Sara Goletto, Ryo Inuzuka and Koichiro Niwa

in Pulmonary Arterial Hypertension

Published on behalf of Oxford University Press

ISBN: 9780199572632
Published online January 2012 | e-ISBN: 9780199607495 | DOI:

Series: Oxford Cardiology Library

Other causes of pulmonary hypertension

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• Patients with HIV and pulmonary arterial hypertension (PAH) have an increased risk of death compared to those without. Bosentan has been shown to improve functional capacity without interfering with antiretroviral drug plasma concentrations • Chronic schistosomiasis is one of the most common causes of PAH in endemic areas. A high index of suspicion is necessary when patients from such areas are presented with symptoms suggesting possible pulmonary hypertension • In patients with portal hypertension, the risk of developing pulmonary arterial hypertension increases with the duration of the disease. Screening for PAH is recommended if liver transplantation is considered • The prevalence of PAH amongst patients with sickle cell disease is about 30% and significantly reduces survival. Right heart catheterization is recommended In suspected cases to confirm the diagnosis of PAH and rule out pulmonary venous hypertension due to left heart disease, which is often present in this population.

Chapter.  1882 words. 

Subjects: Cardiovascular Medicine

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