BPH, PSA, and the risk of having prostate cancer (PCA)

Seife Hailemariam and Lukas Bubendorf

in Benign Prostatic Hyperplasia and Lower Urinary Tract Symptoms in Men

Published on behalf of Oxford University Press

ISBN: 9780199572779
Published online January 2012 | e-ISBN: 9780199607501 | DOI:

Series: Oxford Urology Library

BPH, PSA, and the risk of having prostate cancer (PCA)

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• Benign prostatic hyperplasia (BPH) is a common benign disorder of the prostate that, when advanced, results in varying degrees of urinary obstruction with lower urinary tract symptoms (LUTS) • The disease represents a nodular enlargement of the prostate mainly in the transition zone (TZ) caused by hyperplasia of both glandular and stromal components • It occurs only in individuals with intact testes indicating androgen dependency • Despite topographic and architectural similarities between PCA arising in TZ and atypical adenomatous hyperplasia (AAH) and BPH, there is no convincing evidence linking BPH or AAH to PCA.

Chapter.  1957 words.  Illustrated.

Subjects: Genito-urinary Medicine

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