Renal dysfunction

Darren Green and Philip A. Kalra

in Oxford Textbook of Heart Failure

Published on behalf of Oxford University Press

ISBN: 9780199577729
Published online July 2011 | e-ISBN: 9780199697809 | DOI:

Series: Oxford Textbooks

Renal dysfunction

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Up to 55% of patients with heart failure (HF) have evidence ofchronic kidney disease (CKD) stages 3–5 (estimated glomerular filtration rate (eGFR) of 15–59 mL/min), and mortalityrises in proportion to fall in GFR. 1 In such patients,advanced CKD is as prognostically important as left ventricularejection fraction (LVEF). 2 HF and its treatment may also play animportant role in the pathophysiology of acute kidney injury(AKI), with a further associated risk of adverse outcome.

Cardiovascular disease is the leading cause of death in patients withCKD, and structural cardiac abnormalities are highly prevalent indialysis patients.

Chapter.  8283 words.  Illustrated.

Subjects: Cardiovascular Medicine

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