Chapter

Clinical presentation and assessment of disease activity in lupus nephritis

Venkat Reddy and David Isenberg

in Rheumatology and the Kidney

Second edition

Published on behalf of Oxford University Press

Published in print April 2012 | ISBN: 9780199579655
Published online February 2013 | e-ISBN: 9780191763472 | DOI: http://dx.doi.org/10.1093/med/9780199579655.003.0010

Series: Oxford Clinical Nephrology Series

Clinical presentation and assessment of disease activity in lupus nephritis

Show Summary Details

Preview

1. There is renal involvement in 35–75% of patients with SLE. 2. Relatively few patients develop renal failure and failure of treatment compliance is often a major contributory factor. 3. Defining whether renal abnormalities are due to activity, damage or a combination of both is important in guiding treatment. 4. General activity indices such as the BILAG or SLEDAI scoring systems, together with more specific indicators (e.g. PCR and the presence of urinary red cells and casts) provide an optimal way of assessing disease activity in a patient with lupus nephritis. 5. Renal biopsy remains an essential ‘tool’ in determining the type of lupus involvement, the degree of activity and damage, and the outcome.

Chapter.  4052 words. 

Subjects: Nephrology

Full text: subscription required

How to subscribe Recommend to my Librarian

Buy this work at Oxford University Press »

Users without a subscription are not able to see the full content. Please, subscribe or login to access all content.