Chapter

Systemic therapy for advanced NSCLC, efficacy, and toxicity

Taylor M. Ortiz and Pasi A. Jänne

in Systemic Treatment of Non-Small Cell Lung Cancer

Published on behalf of Oxford University Press

ISBN: 9780199580484
Published online March 2012 | e-ISBN: 9780199607532 | DOI: http://dx.doi.org/10.1093/med/9780199580484.003.0005

Series: Oxford Oncology Library

Systemic therapy for advanced NSCLC, efficacy, and toxicity

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• Palliate symptoms first. • Chemotherapy improves survival over best supportive care. • Some oligometastatic NSCLC is appropriate for aggressive treatment with curative intent. • Personalized therapy based on EGFR mutation status can improve progression free survival and avoid ineffective therapies. • Tailoring biologic and chemotherapies based on tumor histology can maximize treatment efficacy.

Chapter.  4946 words.  Illustrated.

Subjects: Medical Oncology

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