Chapter

Genetics of antibiotic resistance

Sebastian G. B. Amyes

in Antibacterial Chemotherapy

Published on behalf of Oxford University Press

ISBN: 9780199581368
Published online May 2011 | e-ISBN: 9780199607549 | DOI: http://dx.doi.org/10.1093/med/9780199581368.003.0005

Series: Oxford Infectious Diseases Library

Genetics of antibiotic resistance

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• Mutations leading to resistance and the concept of the mutant prevention concentration (MPC). • Bacterial plasmids as the transporters of resistance genes. • The role of transposons and integrons in bringing the correct combination of resistance genes to a bacterium undergoing clinical treatment. • The plasmid–bacterium relationship as a marriage of convenience.

Chapter.  1557 words.  Illustrated.

Subjects: Medical Oncology

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