Chapter

Mechanisms of antibiotic resistance

Sebastian G. B. Amyes

in Antibacterial Chemotherapy

Published on behalf of Oxford University Press

ISBN: 9780199581368
Published online May 2011 | e-ISBN: 9780199607549 | DOI: http://dx.doi.org/10.1093/med/9780199581368.003.0006

Series: Oxford Infectious Diseases Library

Mechanisms of antibiotic resistance

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• How bacteria prevent the antibiotic reaching its target. • The rise in importance of the efflux pumps particularly in the early stages of resistance development. • Antibiotic destruction and modification, the most successful mechanisms of resistance. • The dominance of the β-lactamases. • The ability of the bacterium to change the target of the antibiotic so it no longer binds.

Chapter.  2296 words.  Illustrated.

Subjects: Medical Oncology

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