Microbiology of CF lung disease

Gerd Döring and Dieter Worlitzsch

in Cystic Fibrosis

Published on behalf of Oxford University Press

ISBN: 9780199582709
Published online September 2011 | e-ISBN: 9780199607563 | DOI:

Series: Oxford Respiratory Medicine Library

Microbiology of CF lung disease

More Like This

Show all results sharing this subject:

  • Respiratory Medicine and Pulmonology


Show Summary Details


• Bacterial lung infections are the predominant cause of restricted life expectancy of CF patients • Eradication of bacteria chronically infecting the CF lungs is virtually impossible • Bacteria adapt their genotype and phenotype to the specific lung environment • CF lung infection involves a mixed growth of facultative and obligate anaerobes • Anaerobic growth conditions induce Pseudomonas biofilm formation, reduce the efficacy of the human defence system, and impair the effectiveness of antibiotics • Early therapy at the onset of infection offers the best chance of eradication • Many organisms are either innately resistant to multiple antibiotics or are able to acquire resistance.

Chapter.  4436 words.  Illustrated.

Subjects: Respiratory Medicine and Pulmonology

Full text: subscription required

How to subscribe Recommend to my Librarian

Buy this work at Oxford University Press »

Users without a subscription are not able to see the full content. Please, subscribe or login to access all content.