Metabolic and musculoskeletal effects of CF

Charles Haworth

in Cystic Fibrosis

Published on behalf of Oxford University Press

Published in print September 2010 | ISBN: 9780199582709
Published online September 2011 | e-ISBN: 9780191740442 | DOI:

Series: Oxford Respiratory Medicine Library

Metabolic and musculoskeletal effects of CF

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10–25% of adults with CF have low bone mineral density (BMD)

Risk factors for low BMD include CFTR genotype, male gender, low body mass index (BMI), pulmonary infection/systemic inflammation, pubertal delay, hypogonadism, oral corticosteroid use, vitamin D insufficiency and vitamin K insufficiency

Approximately 10% of adults with CF develop a non-erosive episodic arthritis characterized by painful swelling of the hands, wrists, knees and ankles

Impaired growth in CF is associated with nutritional deficiency, lung infection and systemic inflammation.

Chapter.  3056 words.  Illustrated.

Subjects: Respiratory Medicine and Pulmonology

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