Chapter

Prescribing patterns and determinants of use of antipsychotic long-acting injections: an international perspective*

Tim Lambert

in Antipsychotic long-acting injections

Published on behalf of Oxford University Press

Published in print October 2010 | ISBN: 9780199586042
Published online February 2013 | e-ISBN: 9780191754708 | DOI: http://dx.doi.org/10.1093/med/9780199586042.003.0010
Prescribing patterns and determinants of use of antipsychotic long-acting injections: an international perspective*

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Antipsychotic LAIs continue to have a place in therapy. Although they are prescribed in a significant minority of patients with schizophrenia managed by both general community teams and in inpatient settings, their usage rates vary widely between and within countries and cultures. Whether their use is ‘enough’ or even satisfactory depends on whether adequate numbers of non-adherent patients are being identified first and then treated with LAIs where appropriate. In this chapter we have reviewed the various factors that may influence prescribing rates and considered them within a framework of influences comprising the patient, the model of care, and the nature of the antipsychotics.

Despite our somewhat fragmented knowledge of the associations with LAI use, there remains a significant deficit in our understanding of the consideration for LAI use that occurs at the micro-level of the individual prescriber and/or his or her micro-medical culture. Future research may well benefit from exploring how these issues facilitate or impede the use of these medications in a population with well-established non-adherence, and to promote ways in which the strong evidence base for the role of LAIs in relapse prevention can be better communicated and implemented. The recent establishment of an international educational programme on relapse prevention (CERP) represents a first step in this direction (Lambert et al 2010).

Chapter.  13587 words.  Illustrated.

Subjects: Psychiatry

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