The role of antipsychotic long-acting injections in current practice*

Peter Haddad, Tim Lambert and John Lauriello

in Antipsychotic long-acting injections

Published on behalf of Oxford University Press

Published in print October 2010 | ISBN: 9780199586042
Published online February 2013 | e-ISBN: 9780191754708 | DOI:
The role of antipsychotic long-acting injections in current practice*

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In this chapter we consider the role of antipsychotic long-acting injections (LAIs) in current practice. We start by highlighting the high prevalence of non-adherence with antipsychotics and its consequences in schizophrenia. This is crucial as it is the foundation on which the use of LAIs rests. We examine the benefits of LAIs as well as their disadvantages. Next we review the position of LAIs in schizophrenia treatment guidelines and address the question of when an LAI should be considered as a treatment option. Finally we examine some key clinical questions that relate to the use of LAIs and make some recommendations for future research. Some of these areas have been examined in previous chapters, and we will refer back to these as appropriate. However this chapter provides an opportunity to bring various elements together and provide a broader picture of the place of LAIs in current practice. For the most part we concentrate on schizophrenia given that published data on the use of LAIs in bipolar disorder are limited. As more data become available the role of LAIs in bipolar disorder and other chronic psychotic disorders will become clearer.

Chapter.  9807 words.  Illustrated.

Subjects: Psychiatry

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