Case 28

Joel David, Anne Miller, Anushka Soni and Lyn Williamson

in Oxford Case Histories in Rheumatology

Published on behalf of Oxford University Press

Published in print October 2011 | ISBN: 9780199587506
Published online November 2012 | e-ISBN: 9780191753442 | DOI:

Series: Oxford Case Histories

Case 28

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A 26-year-old woman was referred by her GP with an 8-year history of Raynaud’s syndrome. She described several occasions where she had had infected ischaemic ulcers on her feet. She smoked 15 cigarettes a day and was on the combined oral contraceptive pill. She was seen by the registrar, who noted spindled fingers with distal pulp atrophy. Her fingers and toes were cold and had a dusky blue discoloration. Investigations were arranged and she was advised to stop smoking. Her ENA was positive for anticentromere antibody. Lung function tests showed a reduced TLCO of 72%. The chest CT scan was normal, as was an echocardiogram.

Chapter.  918 words. 

Subjects: Rheumatology

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