Chapter

Cognition in amyotrophic lateral sclerosis

Jennifer Murphy, Fizaa Ahmed and Catherine Lomen-Hoerth

in Amyotrophic Lateral Sclerosis and the Frontotemporal Dementias

Published on behalf of Oxford University Press

Published in print October 2012 | ISBN: 9780199590674
Published online November 2012 | e-ISBN: 9780191753466 | DOI: http://dx.doi.org/10.1093/med/9780199590674.003.0010
Cognition in amyotrophic lateral sclerosis

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This publication is a testament to the now wide acceptance that amyotrophic lateral sclerosis (ALS) is a multisystem disorder affecting extra-motor cerebral areas. The overlap of frontotemporal dementia (FTD) and ALS has been well documented in both patients with FTD with comorbid motor neurone deterioration and patients with ALS with frontotemporal dysfunction. In this chapter the nature and prevalence of frontotemporal dysfunction in ALS is described in a historical context, followed by a review of recent consensus criteria intended to unify the measurement and diagnosis of the overlapping syndromes. Lastly, clinical mimics, effects on survival, and treatment considerations are discussed.

Chapter.  7120 words. 

Subjects: Neurology

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