Managing glycaemia—current oral agents

Roger Gadsby

in Type 2 Diabetes

Second edition

Published on behalf of Oxford University Press

Published in print May 2010 | ISBN: 9780199596171
Published online January 2012 | e-ISBN: 9780191739699 | DOI:

Series: Oxford Diabetes Library

Managing glycaemia—current oral agents

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• Once treatment with lifestyle modification fails to achieve optimal control of glycaemia, oral glucose lowering agents are required. Initially one oral agent is used in monotherapy • If treatment with one agent doesn't achieve optimal glycaemic control a second oral agent can be added in dual therapy • If two agents are not successful, a third can be added, in triple oral therapy • Such combination therapy is possible as there are different groups of agents that lower blood glucose by different mechanisms.

Chapter.  2617 words. 

Subjects: Endocrinology and Diabetes

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