Chapter

Anaphylaxis

Philip Wiffen, Marc Mitchell, Melanie Snelling and Nicola Stoner

in Oxford Handbook of Clinical Pharmacy

Second edition

Published on behalf of Oxford University Press

Published in print January 2012 | ISBN: 9780199603640
Published online January 2012 | e-ISBN: 9780191730610 | DOI: http://dx.doi.org/10.1093/med/9780199603640.003.0003

Series: Oxford Medical Handbooks

Anaphylaxis

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Symptoms and signs of anaphylaxis 26

Treatment of anaphylaxis 28

Prevention of anaphylaxis 31

Anaphylaxis is defined as an immediate systems hypersensitivity event produced by IgE-mediated release of chemicals from mast cells and basophils. Theoretically, prior exposure to the agent is required and the reaction is not dose- or route-related, but in practice anaphylaxis to injected antigen is more frequent, severe, and rapid in onset than following exposure to oral or topical antigen....

Chapter.  1222 words. 

Subjects: Pharmacology

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