Chapter

The relationship between mast cells and histamine

Michael Kaliner

in Landmark Papers in Allergy

Published on behalf of Oxford University Press

Published in print February 2013 | ISBN: 9780199651559
Published online April 2013 | e-ISBN: 9780191754241 | DOI: http://dx.doi.org/10.1093/med/9780199651559.003.0024

Series: Landmark Papers

The relationship between mast cells and histamine

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  • Public Health and Epidemiology
  • Immunology
  • Respiratory Medicine and Pulmonology

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The amount of histamine that can be extracted from various body tissues has been studied extensively in recent years. However, little attention has been paid to the histology of tissues rich in histamine or to the changes which accompany histamine release. Since it is now believed that heparin in all species is produced by tissue mast cells . . . it seemed of interest to determine whether histamine also could arise from tissue mast cells. . . . Further evidence that substantial amounts of histamine are contained in, and can be released by, tissue mast cells is presented in this paper.

Chapter.  1023 words.  Illustrated.

Subjects: Public Health and Epidemiology ; Immunology ; Respiratory Medicine and Pulmonology

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