Chapter

Burnet, clonal selection theory, and acquired immunological tolerance

Sarah Howie

in Landmark Papers in Allergy

Published on behalf of Oxford University Press

Published in print February 2013 | ISBN: 9780199651559
Published online April 2013 | e-ISBN: 9780191754241 | DOI: http://dx.doi.org/10.1093/med/9780199651559.003.0026

Series: Landmark Papers

Burnet, clonal selection theory, and acquired immunological tolerance

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Medicine has been the mother of all the biological sciences. There are many reasons for this, but one of them is specially relevant to my present topic. It is simply that while the body functions smoothly things are taken for granted. It is only when things go wrong that it becomes possible to perceive that there is something in normal function which requires understanding. The central theme of these lectures is that the phenomena seen clinically in diseases of the so-called auto-immune group can be interpreted to throw light on the nature of immunological processes, and equally that recent developments in theoretical immunology are becoming highly relevant to clinical medicine.

Chapter.  1066 words.  Illustrated.

Subjects: Public Health and Epidemiology ; Immunology ; Respiratory Medicine and Pulmonology

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