Chapter

Disodium cromoglycate for allergic asthma

Alan Edwards

in Landmark Papers in Allergy

Published on behalf of Oxford University Press

Published in print February 2013 | ISBN: 9780199651559
Published online April 2013 | e-ISBN: 9780191754241 | DOI: http://dx.doi.org/10.1093/med/9780199651559.003.0030

Series: Landmark Papers

Disodium cromoglycate for allergic asthma

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  • Public Health and Epidemiology
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A double-blind cross-over sequential trial of a new antiallergic compound, disodium cromoglycate (‘FPL670’, ‘Intal’) was carried out over a period of 6 weeks in ten patients severely disabled with allergic bronchial asthma. There was a significant clinical improvement during administration of FPL670 plus isoprenaline in all patients compared with two periods in which isoprenaline alone was given. Spirometric improvement occurred in only four patients. Subsequent experience over periods up to 26 months with these and other patients has confirmed the therapeutic value and safety of FPL670 in the management of allergic bronchial asthma.

Chapter.  1156 words. 

Subjects: Public Health and Epidemiology ; Immunology ; Respiratory Medicine and Pulmonology

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