Chapter

Ancient Egyptian soup for treating asthma: Cox and Intal

Anant Parekh

in Landmark Papers in Allergy

Published on behalf of Oxford University Press

Published in print February 2013 | ISBN: 9780199651559
Published online April 2013 | e-ISBN: 9780191754241 | DOI: http://dx.doi.org/10.1093/med/9780199651559.003.0031

Series: Landmark Papers

Ancient Egyptian soup for treating asthma: Cox and Intal

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Chromone derivatives exhibiting unusual biological activity have been studied in these laboratories for several years. One of these, disodium cromoglycate (FLP670), has been found to inhibit specifically the liberation of the mediators of anaphylaxis initiated by the interaction of antigen with regain type antibodies. It is neither a bronchodilator nor an anti-inflammatory agent and its action is distinct from that of corticosteroids. In experiments on an asthmatic volunteer, inhaling the compound inhibited the acute effect of subsequent antigen inhalation. In patients suffering from allergic asthma, inhalation of this compound was followed by clinical improvement.

Chapter.  1022 words. 

Subjects: Public Health and Epidemiology ; Immunology ; Respiratory Medicine and Pulmonology

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