Chapter

Penicillin allergy: a model for practical clinical translational science

Lanny Rosenwasser

in Landmark Papers in Allergy

Published on behalf of Oxford University Press

Published in print February 2013 | ISBN: 9780199651559
Published online April 2013 | e-ISBN: 9780191754241 | DOI: http://dx.doi.org/10.1093/med/9780199651559.003.0034

Series: Landmark Papers

Penicillin allergy: a model for practical clinical translational science

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Direct skin tests and passive transfer tests were compared as to their abilities to detect skin-sensitizing antibody (SSA) to penicillin haptens in man. Direct skin tests were found to be a generally more sensitive detector of SSA. However, in some cases where penicillin therapy had been given recently, and the immune response to penicillin was still evolving, direct skin tests were negative in the face of positive passive transfer tests of the same specificity.

Chapter.  1434 words. 

Subjects: Public Health and Epidemiology ; Immunology ; Respiratory Medicine and Pulmonology

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