Chapter

Allergic reactions to colloid infusions—another chapter in the colloid debate

Jasmeet Soar

in Landmark Papers in Allergy

Published on behalf of Oxford University Press

Published in print February 2013 | ISBN: 9780199651559
Published online April 2013 | e-ISBN: 9780191754241 | DOI: http://dx.doi.org/10.1093/med/9780199651559.003.0046

Series: Landmark Papers

Allergic reactions to colloid infusions—another chapter in the colloid debate

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All available colloid volume substitutes carry the risk of anaphylactoid reactions. In a multicentre prospective trial, 69 cases of anaphylactoid reactions have been observed among 200,906 infusions of colloid volume substitutes. The frequency of severe reactions (shock, cardiac and/or respiratory arrest) was 0.003% for plasma-protein solutions, 0.006% for hydroxyethyl starch, 0.008% for dextran, and 0.038% for gelatin solutions. . . . Comparing the risks with the beneficial effects of colloid volume substitutes we can safely state that the clinical use of these substances is surely justified.

Chapter.  1320 words. 

Subjects: Public Health and Epidemiology ; Immunology ; Respiratory Medicine and Pulmonology

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