A new way of considering ‘quality of life’

Allison Worth

in Landmark Papers in Allergy

Published on behalf of Oxford University Press

Published in print February 2013 | ISBN: 9780199651559
Published online February 2013 | e-ISBN: 9780191754241 | DOI:

Series: Landmark Papers

A new way of considering ‘quality of life’

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  • Public Health and Epidemiology
  • Immunology
  • Respiratory Medicine and Pulmonology


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Instruments to measure symptoms of rhinoconjunctivitis are used commonly in clinical trials in rhinoconjunctivitis. However, these questionnaires do not address the overall impact of the symptoms on patients’ day-to-day lives. In response to the need for a more sophisticated instrument for measuring health-related quality of life in clinical trials in rhinoconjunctivitis we developed Quality of Life Questionnaire (RQLQ) . . . In this paper we describe the developmental process for the RQLQ and present data regarding the reproducibility, responsiveness and validity of the questionnaire . . . The aim was to develop an evaluative instrument capable of measuring change over time within people . . . . . . although the issues of greatest concern to patients with rhinoconjunctivitis are the symptoms which are traditionally measured, in almost all patients the condition has a deleterious impact on a number of aspects of their lives. Almost all patients experience important degrees of systemic symptoms, impairment of sleep, limitation of activities, and emotional distress as a result of their rhinoconjunctivitis. Any attempt to measure the full impact of the condition, or its treatment, must consider these other factors.

Chapter.  1510 words. 

Subjects: Public Health and Epidemiology ; Immunology ; Respiratory Medicine and Pulmonology

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