Testosterone and the brain

Bradley D. Anawalt

in Testosterone Deficiency in Men

Second edition

Published on behalf of Oxford University Press

Published in print December 2012 | ISBN: 9780199651672
Published online December 2012 | e-ISBN: 9780191742958 | DOI:

Series: Oxford Endocrinology Library

Testosterone and the brain

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Testosterone and its metabolites have important effects on neural development and specific behavioural and cognitive responses. Serum testosterone levels may have a U-shaped relationship to male cognitive function; higher and lower serum testosterone levels may be associated with worse function. In hypogonadal men, testosterone therapy improves cognitive function, mood, and libido. At usual dosages, testosterone does not increase aggression. It is unknown if testosterone supplementation to ageing men with declining testosterone levels might prevent cognitive decline and dementia.

Chapter.  2387 words. 

Subjects: Endocrinology and Diabetes

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