Principles of Epilepsy Surgery

Samden D. Lhatoo

in Oxford Textbook of Epilepsy and Epileptic Seizures

Published on behalf of Oxford University Press

Published in print December 2012 | ISBN: 9780199659043
Published online December 2012 | e-ISBN: 9780191751363 | DOI:

Series: Oxford Textbook of

Principles of Epilepsy Surgery

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  • Neurology
  • Neurosurgery
  • Surgical Skills


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The modern practice of epilepsy surgery involves multi-modal pre-surgical investigations such as surface and intra-cranial EEG, high resolution structural imaging and advanced functional imaging although the clinical analysis of seizures remains an important tool. A multidisciplinary approach is required, including close collaboration between neurologists, neurophysiologists, neurosurgeons, neuroradiologists, neuropsychologists, and neuropsychiatrists. Resective surgery in the refractory focal epilepsies offers significant chances of seizure freedom in temporal as well as extra-temporal lobe epilepsies provided patients are carefully selected, investigated and their eloquent cortex stringently identified prior to resection. For some patients who are not candidates for such surgery, vagal as well as deep brain stimulators may offer further options. In this chapter, we discuss the principles on which modern epilepsy surgical practice is based.

Chapter.  5498 words.  Illustrated.

Subjects: Neurology ; Neurosurgery ; Surgical Skills

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