Chapter

Opioid pharmacogenomics

Cathy Stannard, Michael Coupe and Anthony Pickering

in Opioids in Non-Cancer Pain

Second edition

Published on behalf of Oxford University Press

Published in print March 2013 | ISBN: 9780199678075
Published online March 2013 | e-ISBN: 9780191757464 | DOI: http://dx.doi.org/10.1093/med/9780199678075.003.0004

Series: Oxford Pain Management Library

Opioid pharmacogenomics

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Pharmacogenomic phenotypes account for some of the inter-individual variations in opioid response. This is best exemplified by variations in the metabolic pathways for codeine and tramadol. There are common functional variants in opiate receptors, but, as yet, the clinical significance of these polymorphisms is uncertain.

Chapter.  1261 words. 

Subjects: Clinical Oncology ; Clinical Pharmacology and Therapeutics ; Pain Medicine

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