Chapter

Contraindications, cautions, and drug interactions

Cathy Stannard, Michael Coupe and Anthony Pickering

in Opioids in Non-Cancer Pain

Second edition

Published on behalf of Oxford University Press

Published in print March 2013 | ISBN: 9780199678075
Published online March 2013 | e-ISBN: 9780191757464 | DOI: http://dx.doi.org/10.1093/med/9780199678075.003.0009

Series: Oxford Pain Management Library

Contraindications, cautions, and drug interactions

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There are few absolute contraindications to opioid use. Renal and hepatic disease can result in significant alterations in drug handling, and dose reductions may be required. Opioids have a number of important drug interactions, which can result in altered pharmacokinetics or pharmacodynamics.

Chapter.  1111 words. 

Subjects: Clinical Oncology ; Clinical Pharmacology and Therapeutics ; Pain Medicine

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